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Game of Pain, part 1: CBD hope?

Why Jake Plummer and others are pushing for research on CBD’s benefits to NFL players

By Nicki Jhabvala

Nestled at the base of the Flatirons and tucked behind a dog park is Jake Plummer’s oasis, a row of three-wall handball courts at the East Boulder Community Center. It’s 9:30 a.m. on a Saturday and he has just arrived on his silver Giant bicycle decorated in stickers of local breweries to the sound of a rubber ball beating against the concrete wall — TH-WAP, TH-WAP, TH-WAP — and the beat with Bob Dylan’s “Knockin’ on Heaven’s Door” humming from a wireless speaker.

“Hey, Mr. Jake Plummer!” a man shouts as Plummer leans his bike on a tree, unstraps the small Denver Broncos cooler carrying a couple cans of Pilsner and shakes a few hands. Here the former Broncos quarterback is a regular among a group of about 20 players from their mid-20s to well into their 70s.

“It’s hard with these young cats,” Plummer said as he straps on his goggles and tightens his gloves. “I’ll go til I’m stiff. Maybe two or three games.”

Plummer credits yoga for helping keep him on the court. And visits to a chiropractor. The jogging and cycling. The acupuncture. Even the dry needling he started.

But especially cannabidiol, or CBD, a nonpsychoactive compound in cannabis that gained notice a few years ago in treating epilepsy in children and has been shown to have anti-inflammatory and pain-relieving properties.

Plummer and many other retired and active NFL players believe the compound is an effective alternative to the potent painkillers they receive while in the league, and that players should be allowed to use it.

So he and four other ex-NFL players, as well as one current one, have teamed with a Colorado hemp producer and its partnering non-profit to raise money for research to find out if CBD is a safe and viable treatment for not only pain but also symptoms of concussions and chronic traumatic encephalopathy (CTE).

The mission of their campaign — “When the Bright Lights Fade” — isn’t necessarily to advocate for the NFL’s approval of marijuana, though many believe weed should be legal for players to use, but to first work with researchers at Johns Hopkins University and the University of Pennsylvania to study football players’ use of cannabinoids and the body’s tolerance of them long term.

“Do we have the silver bullet? Do we have the remedy? I don’t know,” Plummer said. “I sure would like to find out.”

Seeking safer alternatives

Throughout his 10-year career as an NFL quarterback, Plummer was cognizant of the physical and mental pain he was inflicting on himself. As much as he tried to avoid painkillers, there were times when he needed the assistance.

“There were guys in college that were taking Percocets all the time and drinking beers,” he said. “It was rampant. I had done that a few times, but the effects afterward, the day after, just the feeling I had, I hated it. It made me feel detached. In 10 years (in the NFL), I took maybe 20, where I could come out of a game and be like, ‘I need to make this flight home, because it hurts like hell just sitting here.’ But if I had had (CBD), I would have much rather have done that.”

Others would too.

Former Broncos tight end Nate Jackson has spoken candidly of the abuse his body took playing football. Torn ligaments. Torn muscles. Broken bones. Chipped bones. Separated shoulders. A dislocated shoulder. Misaligned clavicles. Lower spine trauma. Brain trauma. And more.

He was the first player to get involved with the Bright Lights campaign, joining CW Botanicals and the Realm of Caring, its non-profit partner for cannabinoid advocacy and education. He did it not because he wants NFL locker rooms to become smoke-filled retreats with trainers handing out joints. He simply wants players to have options — effective but safer options than the prescription painkillers and illegal drugs he admittedly used in desperation when he played.

CBD, he believes, is one.

“I didn’t take Vicodin or Percocet before practices or games,” Jackson said. “It was not something that I wanted to try because football is too much. It’s too violent. You got 11 guys coming to take your head off, so I didn’t want to chance it.”

Pills and injections are the norm in football and the long-term health concerns are great. Players have often cited the unwelcome side effects — lethargy, depression, stomach pain, the risk of addiction — and some have chosen to self-medicate instead, often with marijuana.

Last summer, Plummer added CBD to his regimen. He ingests the oil and rubs the gel on his wrists and back. He doesn’t get high, but he is able to play two to three games of handball with “the young cats.”

“I’ve used every tincture and fad known to man that comes through to claim pain relief,” he said. “This one really does give me some relief in the area of discomfort.”

Anecdotal evidence and preclinical research, often on animals, suggest CBD is effective in treating neuropathic pain and inflammation without getting users high; tetrahydrocannabinol, or THC, is the psychoactive ingredient in cannabis.

“We’re talking about something with a safety profile that looks like vitamin C, but because it comes out of the controversial world of cannabis, people immediately associate it with a dangerous drug,” said Joel Stanley, the CEO of CW Botanicals. “Nothing could be farther from the truth.”

CW’s product, called Charlotte’s Web, is made from hemp, distinct from marijuana and legally defined as having no more than 0.3 percent THC. It’s believed that no player could consume enough of the product to cross the NFL’s allowable limit of 35 nanograms of activated THC per milliliter of blood. But any amount poses a risk.

“These guys, if they want to just take care of their bodies, they can’t out of fear that they would test positive,” said Ryan Kingsbury, CW’s chief communications officer. “If they test under it, it’s not a big deal. I’m confident it won’t, but I don’t want to tell a guy who has a multi-million-dollar deal that it won’t.”

Kingsbury estimates at least 30 active and retired players use some form of CBD from CW Botanicals, with the former group clearly believing the rewards outweigh any risks.

Painful lifestyle

As more states — up to 24 now, plus the District of Columbia — have legalized medical marijuana, calls for the NFL to change its substance-abuse policy have grown louder.

The league and the players association, which both declined to grant interviews for this story, agreed to alter the policy in 2014 and raise the THC threshold from 15 ng/mL to 35 ng/mL. Players are tested only once in the offseason, but violators are entered into an intervention program that calls for additional random tests and penalties that range from fines to one-year suspensions without pay.

In the context of a 16-game season, the penalties are severe.

“Do you ever hear any of other professional athletes getting popped for weed other than in football? You never do,” said Jackson, who estimates at least 50 percent of NFL players use some form of marijuana. “It’s really not happening anywhere but in the NFL, and it’s funny because the NFL is really the one sport that needs it most. (Players) use it because they need it, and it’s not stopping them from being the very best at what they do. Why are we punishing them for it?”

Plummer said change can’t be demanded without more science, so part of the Bright Lights’ initial studies will focus on how much CBD a player can consume without testing hot.

But the “what ifs?” are there: What if the NFL simply raised its THC limit to ensure those taking hemp-based CBD products wouldn’t fail a test? What if CBD could be prescribed by team trainers via a therapeutic-use exemption?

After all, that exemption is how former offensive lineman Eben Britton was allowed to take Adderall, a medication that helped with pain from injuries but took him on an emotional roller coaster. In 2013, his first year with the Chicago Bears, Britton suffered a torn muscle on the bottom of his right foot. He still has no feeling in that foot. His shoulder was dislocated. And by the end of every season, he would have to wear casts on his thumbs and now has arthritis in his fingers. He has pain in nearly every joint.

“Every guy on the team is a prescribed a bottle of anti-inflammatories of one kind or another, whether it’s Cataflam, Indocin, Aleve, Tylenol, Advil. Every guy is taking that (stuff) every single day,” Britton said.

Baltimore Ravens offensive tackle Eugene Monroe saw up close how much Britton struggled when they were teammates with the Jacksonville Jaguars. He remembers the play thatblew out Britton’s shoulder at Kansas City, and he remembers when Britton walked around Jaguars headquarters with an IV drip for eight weeks after contracting an infection following back surgery.

“You’ll find these stories across every locker room in the NFL,” Monroe said. “When you talk to someone’s family members, if you talk to a player’s wife, I guarantee you, she’d be able to paint a vivid picture for the struggles that her husband goes through on a daily basis. I’m talking about out of season too, because injuries don’t magically go away.”

Monroe, the only active player involved in the campaign, said he has never used marijuana or CBD. He donated $10,000 to the cause, but he can’t and won’t risk failing a drug test.

“It’s hard to read how beneficial CBD is and not be able to take it, knowing that all of the symptoms that I’m experiencing as an athlete could potentially, or will be, remedied because it’s happened over and over again for people all over our country,” he said. “There’s no reason for the NFL or other sports to test their players and punish them for consuming a substance that is benefiting them.”

Players in a catch-22

Mark Schlereth, a former Broncos guard who is an NFL analyst on radio and TV, never used marijuana or CBD while playing — and still doesn’t. He never smoked, or drank alcohol. He took team-prescribed painkillers when needed, but only when needed.

He left the NFL in 2001 with three Super Bowl title rings, a body that was relatively intact despite numerous surgeries and a lucrative second career awaiting him, at ESPN.

But he hasn’t been pain free for a long time.

“I haven’t known anything but pain from the time I was 18 years old,” he said. “I wake up 10 times a night because my shoulder hurts or my back hurts or my knee is bothering me. I don’t know what it’s like to lay my head on a pillow at night and wake up the next morning without waking up eight to 10 times. That’s normal to me. And I think most guys find whatever normal is and you just kind of adjust to it.”

Schlereth said the NFL became more regulated in how it administered prescription painkillers about midway through his 12-year career. But rules alone haven’t spared addiction.

In 2014, a record 47,055 deaths from drug overdoses occurred in the U.S., and opioids were involved in a record 28,647 (61 percent) of those, according to the Centers for Disease Control and Prevention. Vicodin, Percocet, morphine, codeine — drugs often given to NFL players to relieve pain — are part of a nationwide epidemic.

Players often are in a Catch-22: They need the drugs to stay on the field, and to stay on the team. But in taking them, they run a high risk of becoming addicted and further destroying their long-term health.

“Guys abuse opiates and painkillers and everything else,” Schlereth said. “So if there’s compelling research that says (CBD) is helpful, I don’t know why the NFL wouldn’t want to help players.”

A 2011 study by researchers at Washington University in St. Louis and commissioned by ESPN found that 52 percent of retired NFL players used opioids during their career and 71 percent of those reported abuse.

It’s unlikely for someone to die of a cannabis overdose, let alone nonpsychoactive CBD.

“Opioids can cause a fatal overdose — morphine, heroin, oxycodone — because if you take too much, those molecules bind to the receptors in the brainstem and prevent you from breathing,” said Dr. David Casarett, a physician and researcher at the University of Pennsylvania and the author of “Stoned.” “But since there are no cannabinoid receptors in the brainstem, marijuana won’t. You could certainly have a really interesting couple of hours — hallucinations, paranoid delusions, the whole bit — but you won’t die because of an overdose.”

Several studies have found CBD even counteracts the psychoactive effects of THC and could be beneficial in treating some addictions.

But it doesn’t mean it works for all. And it doesn’t mean it’s free of side effects. Any long-term ones are unknown.

“I wouldn’t stake my entire reputation on saying that it works, but there are a lot of researchers who think that of all the ingredients in marijuana, it might be CBD that has much or even more of an effect on that neuropathic pain than THC does,” Casarett said. “As far as I know, there really haven’t been studies on brain trauma except for some very preliminary laboratory studies — studies that cannabinoids may be protective after strokes induced in mice in the laboratory. That’s a huge leap to say there’s cellular evidence of neuroprotection in a mouse in a laboratory, so we should start giving it to football players.”

Looking ahead

Plummer was a rarity in his day. While countless players are forced out of football by injury, he voluntarily left the NFL at age 32.

“I was lucky,” he said. “I didn’t want to have a bad (injury) at that point in my life and my career. I don’t think I could have made it through it.”

In recent years, players have begun to look ahead, just as Plummer did nine years ago, primarily because of an increased focus on concussions and subsequent brain damage.

Just over a year ago San Francisco 49ers linebackerChris Borland retired after only one season at age 24because of head injuries. Green Bay Packers rookie wide receiver Adrian Coxsoncalled it quits six months later having never played in a regular-season game because he feared one more hit could “possibly kill me or be life-damaging.” (A month earlier he had been taken off the practice field by an ambulance with a Grade 3 concussion.) And this month, Buffalo Bills linebacker A.J. Tarpley announced his retirement at age 23 after playing only one season in the NFL, also citing concussions.

Talk of brain injuries and CTE has reached a fever pitch in the NFL, but research and knowledge of the disease still is in its infancy. The same holds true for CBD, only funding for its research pales in comparison. The players involved in the Bright Lights campaign hope the early studies that are funded will spur a larger clinical examination of CBD’s effectiveness in treating not just injuries but also symptoms of concussions and CTE.

Plummer hopes he and his fellow players will soon be armed with enough clinical proof of CBD’s benefits to initiate a conversation with NFL officials. And he really hopes for change — change that will help other players be able to hit the courts with the “young cats” ’til they’re stiff. Maybe go two or three games.

“We’re hoping (NFL officials) talk to us about it if they really, truly care about the players and their health and well-being — not just while they’re making millions of dollars from the NFL, but when they’re done and when they’ve moved on,” Plummer said. “Joe Montana can’t live an active lifestyle, Jim McMahon has headaches all the time and is in pain. These are the legends who prance out at halftime during the 50th Super Bowl, and they’re suffering. People don’t know that, but when they read about it and see it, that’s when I hope there’s action taken.”



Selling legal weed: It's all about the packaging

Bloomberg Alexandria Arnold

Soon after voters in Washington state green-lighted sales of recreational pot, Winterlife Cannabis made the pivot into home delivery. It wasn't exactly a legal business decision back then, in the months before state regulators had worked out all the rules. Winterlife spread the word on Craigslist, and employees adopted wildlife-inspired code names—spotted skunk, crow, platypus—while selling plastic baggies filled with distinct varieties of marijuana. 

Fast-forward more than three years, and Winterlife is a fully licensed cannabis processor with a diverse product line and more sophisticated branding. The company's THC-infused cookies come in professionally designed boxes that stand upright behind countertops or on shelves, a bit of package engineering made necessary by state rules for marijuana retailers. The old critter code names have evolved into polished illustrations, each animal now dressed in a Prohibition-era hat. In other words: basic branding. The product logos aren't rendered as simple cartoons—that would be illegal, akin to using Joe Camel on cigarettes. Another sales regulation dictating the minimum thickness of interior plastic packaging forced Winterlife to ditch its once-compostable wrappers.

By following these regulations and embracing carefully considered packaging, pot startups have effectively left behind the ramshackle trappings of the black market. “There’s a place for the tie-dye, and there are people who really love that,” said Charity Cox, co-founder and creative director of Winterlife. “But if we really want people to see this as an alternative to alcohol or just another way to kick back and relax, you can’t just focus on what has been.”

As marijuana legalization and commerce spreads in the U.S., a new breed of cannabis ventures is trying to figure out how to draw in new customers—and packaging is key. Make your products look like they could be sold by Girl Scouts or Whole Foods, and pot manufacturers can assuage concerns about safety and social acceptance. Seattle is blazing the way, with entrepreneurs commissioning an eye-catching array of packages that are both beautiful and law-abiding. Mr. Moxey's Mints, for example, come in pressed-tin boxes that are reminiscent of Altoids, except for a band affixed to the box with the following warning:

"When eaten or swallowed, the intoxicating effects of this drug may be delayed by two or more hours. This product may be unlawful outside of Washington State."

In addition to such warnings, marijuana products sold in Washington are obliged to feature the equivalent of nutritional information boxes. Labels must show an inventory ID number assigned by the state's liquor control board, concentrations of active agents in marijuana known as THC and CBD, net weight, and the date of harvest. Cannabis-infused food products also note a best-by date, date of manufacture, and complete list of ingredients and major allergens.

Wannabe pot entrepreneurs came out of the woodwork after voters in Washington and Colorado became the first to legalize sales of recreational weed in November 2012. Some businesses wrongly assumed they would automatically strike it rich by getting in early. The reality was that marketing mattered, particularly to people whose last experience with pot was a party decades ago. 

"In the beginning, it was very difficult to get clients, because we didn’t have any marijuana marketing experience. And then, of course, the marijuana companies did not see a need to market,' said Olivia Mannix, co-chief executive of Cannabrand, a Denver marketing agency dedicated to the marijuana industry. "One to two years later, the tables have completely turned and the market is very competitive."

For Winterlife, packaging helped complete the transition from a delivery service at risk from law enforcement into a legitimate producer with pot products in more than 50 stores across the state, from Bellingham to Vancouver. One retail location, Uncle Ike's Pot Shop in Seattle's gentrifying Central District, feels a lot like a bar from the outside, with two bouncers clad in black barring anyone under 21. Inside the well-lit shop, first-time buyers can peruse a menu-like handout while waiting in line for a "budtender." All the products are stowed behind a wraparound glass counter. It becomes clear, from the other side of the counter, that distinctive packaging is the only way to stand out on the packed shelves.

The packaging is also used to convey information about pot dosage — or, in some cases, to conceal from onlookers that the product contains pot. Botanica Seattle, the company behind Mr. Moxey's Mints, uses sleek, minimalist black pouches for its Spot Chocolate brand. One big colorful circle on the front boldly declares the strain and potency of the pot blended into the bonbon. 

"We didn't overthink it," said founder Tim Moxey. "It wasn't supposed to do anything but say, 'There's 5 milligrams of sativa.' " The mints, on the other hand, are sold in containers with a subtle, incognito aesthetic. The design "should be something they could carry and it wouldn't give themselves away.'

Zoots, a brand of low-dose pot treats including berry-flavored nuggets, comes in packaging that the product's co-founder Patrick Devlin hoped would convey consistency and quality. The look was the work of a Portland, Ore., ad agency that's done work for a long list of grocery store staples, such as Tofurky, and the bold wrappers and tins would easily blend into the shelves of any mini-market—if that were allowed.

“We want it to look like a normal consumer product,' Devlin said. “We don’t want it to look druggy.”

To contact the author of this story: Alexandria Arnold in Seattle at  To contact the editors responsible for this story: Aaron Rutkoff at, David Scheer at 

©2016 Bloomberg L.P.


DEA Plans To Decide Whether To Reschedule Marijuana By Mid-Year

The agency gave no clue whether it will remove pot from its Schedule 1 category of dangerous drugs.

Noelle Skodzinski

Editor's Note: In light of Huffington Post's report (below) about the DEA's plans to decide by mid-year whether or not marijuana's classification should be changed from a Schedule I to a Schedule II drug, Cannabis Business Times (CBT) reached out to the Marijuana Policy Project (MPP) for the organization's insights on what a reclassification would mean for legal marijuana businesses — mainly, would state-legal medical marijuana businesses finally have access to banking/financing services? What about state-legal recreational businesses?

Robert J. Capecchi, Director of Federal Policies for the MPP, told CBT, "My reading of the federal racketeering laws is that banks may be liable for doing business with funds that they know have been derived from a criminal offense, and a rescheduling will not automatically mean marijuana businesses are no longer violating federal criminal law.Under the CSA, even manufacturers and distributors of schedule II, III, IV, or V substances must obtain a registration from the US attorney general, which marijuana businesses do not have. It would seem that unless they obtained that registration, a bank would still be prohibited from accepting their funds because they derived from a federal criminal offense," he said.

"All that said," Capecchi added, "MPP believes that marijuana should be removed from the list of controlled substances all together. Alcohol and tobacco, substances that are far more dangerous than marijuana are not in the CSA, and we feel as if marijuana should be removed from it as well.

"Finally, it should be noted that the letter does not state that the determination will be announced by July, just that the DEA hopes to announce by the end of the first half of the year." he added.
 "Also, the fact that a determination has been made does not mean that they have determined to move marijuana out of schedule I; it could be that the the determination is to keep marijuana in schedule I (which has been the result of every marijuana rescheduling petition that has gone before this one)."
Taylor West, deputy director of the National Cannabis Industry Association, agrees that moving marijuana to a Schedule II classification is not enough. "At this point, only moving marijuana to Schedule II is just not appropriate or objectively supportable by the science. Schedule II includes substances like cocaine and meth, and a move to Schedule II would not substantially change the status of current marijuana laws, businesses, or consumers. It’s not clear that it would have any positive impact on the banking situation, and it would definitively NOT fix the Section 280E tax situation. (Section 280E explicitly applies to both Schedule I and Schedule II substances.)," she said.
"The one main benefit of a move to Schedule II is a slight loosening of the restrictions around medical research, and that is certainly positive. But given the current state of cannabis science, the cannabis industry, and public opinion, the minimum appropriate move would be to Schedule III," West noted. "The move that would truly reflect reality is to deschedule marijuana altogether, treating it similarly to alcohol and allowing states to determine their approach." 

From the Huffington Post's report:
The Drug Enforcement Administration plans to decide whether marijuana should be reclassified under federal law in “the first half of 2016,” the agency said in a letter to senators.
DEA, responding to a 2015 letter from Sen. Elizabeth Warren (D-Mass.) and seven other Democratic senators urging the federal government to facilitate research into marijuana’s medical benefits, doesn’t indicate whether it will reclassify marijuana as less dangerous.
The U.S. has five categories, or schedules, classifying illegal drugs or chemicals that can be used to make them. Schedule I is reserved for drugs the DEA considers to have the highest potential for abuse and no “current accepted medical use.” Marijuana has been classified as Schedule I for decades, along with heroin and LSD. Rescheduling marijuana wouldn’t make it legal, but may ease restrictions on research and reduce penalties for marijuana offenses.